Sulfur in glucosinolate induces enzyme expression and activates detoxification
Cruciferous vegetables like broccoli, cauliflower, cabbage, and Brussels sprouts have been shown to reduce the risk of several degenerative diseases and conditions. The benefits of a diet rich in these vegetables have been well-documented in the medical literature for cardiovascular disease and cancer. What scientists are excited about now is a unique organic compound called glucosinolate, which is made from several plant amino acids and glucose. Glucosinolate contains high amounts of sulfur and nitrogen.
In particular, the sulfur-containing part of plant cells in broccoli has been demonstrated to be an indirect antioxidant. According to a 2012 study published in Frontiers in Genetics, sulforaphane, as the compound is called, has an incredible ability to get certain enzymes to express. This is done by signaling genes in the cell nucleus. These particular enzymes activate the detoxification and antioxidant process. Over the past ten years, scientists have watched sulforaphane do this in vivo, meaning live, in humans. Sulfur heals.
Sulfur works through redox reactions and altering the cellular environment
How does sulfur work as an antioxidant and detoxifier in the human body? The molecules in sulforaphane work via a process known in biochemistry as a redox reaction. Redox is a nickname for oxidation-reduction reactions. A redox reaction is when two chemical compounds exchange electrons. One molecule gives electrons, while the other molecule receives electrons. This is the chemical reaction which occurs when an alkaline molecule gives negatively charged electrons to acidic molecules in order to neutralize the acid. While many antioxidants do this, sulforaphane also alters the epigenetic endpoints.
The field of epigenetics, the cellular environment surrounding genes, is exploding. This discovery with sulforaphane has tremendous possibilities for people with modified genetics and suggests the possibility that genetic diseases may be able to be corrected. A 2011 doctoral dissertation presented by John D. Clarke for a doctorate in molecular and cellular biology proved that a diet rich in broccoli sprouts was able to prevent prostate cancer. Dr. Terry Wahls, M.D. was able to reverse multiple sclerosis without pharmaceuticals by eating a diet high in organic sulfur-rich foods, including broccoli. Others are experiencing similar results.
Sources for this article include:
Pubmed.gov, “Induction of phase 2 antioxidant enzymes by broccoli sulforaphane: perspectives im maintaining the antioxidant activity of vitamins A, C, and E.” S. Boddupalli, et al. Frontiers in Genetics 2012; 3:7. http://www.ncbi.nlm.nih.gov/pubmed/22303412
Chemistry.co.nz, “Redox Reactions: Introduction” http://www.chemistry.co.nz/redox_begin.htm
OregonStateUniversity.edu, “Prostate Cancer Prevention With Broccoli: From Cellular to Human Studies,” by John D. Clarke, doctoral candidate for PhD in Molecular and Cellular Biology, April 28, 2011
Terry Wahls.com, “Up From the Chair: Defeating Progressive MS Without Drugs”
About the author:
This article is provided courtesy of Donna Earnest Pravel, owner and senior editor of Heart of Texas Copywriting Solutions.com. Get free biweekly tips on natural healing and herbs by visiting her blog, Bluebonnet Natural Healing Therapy.
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