The serotonin hypothesis was junk science to begin with.
95 percent of the “brain” neurotransmitter serotonin is in the bowel, and it stops dreaming and psychedelic experiences in their tracks when it accumulates in the brain.
The less serotonin in the brain, the less we need to sleep.
The more serotonin in the brain, the more we need to sleep.
Adano Ley (Swami Nitty-Gritty) encouraged wakefulness and 24-hour consciousness.
He never explained (to me, at least) if this meant (1) exorcising serotonin from the brain or (2) remaining conscious despite the serotonin buildup in the brain.
Complicating the investigation of neurotransmitters is the recent discoveries of mega-neurotransmitters in the brain …
carbon monoxide, nitric oxide, hydrogen sulfide
The “spiritual” investigation of consciousness is still in its infancy, and most everything we know about it derives from medical research.
In other words, Rick Strassman, M.D., author of DMT: The Spirit Molecule, is a documented member of the Medical Priesthood, and we should hold that against him. :/