Dotage & Yellow Fat Disease
Why did biological gerontologists (the eggheads who study why people age) think lipofuscin was irrelevant to aging?
Because there was so much of it — as much as 20% of cellular mass.
Isn’t that a lot like thinking cars are irrelevant to traffic because there are too many of them?
Or like thinking pigeons are irrelevant to pigeon droppings because the sky is filled with them?
But that’s how medical technocrats think — with the south end of their anatomy.
It’s probably because of all the omega 3 fatty acids (DHA, EPA, and ALA) in the north end of their anatomy.
Yellow Fat Disease is an equal opportunity youth-snatcher.
According to Wikipedia (“Lipofuscin,” Jun. 10, 2017) …
“Pathological accumulation of lipofuscin is implicated in Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis, certain lysosomal diseases, acromegaly, denervation atrophy, lipid myopathy, chronic obstructive pulmonary disease, and centronuclear myopathy. Accumulation of lipofuscin in the colon is the cause of the condition melanosis coli.”
Wikipedia (Aug. 16, 2017) goes on to blame melanosis coli — WRONGLY — on senna and aloe vera.
G. Nusko, et al. (“Melanosis coli—a harmless pigmentation or a precancerous condition?,” Zeitschrift Fur Gastroenterologie, May, 1997) wrote …
“CONCLUSION: There appears to be no association between colorectal cancer and melanosis coli or laxative use.”
Wikipedia missed the memo (20 years ago).
According to Wikipedia (“Brown atrophy of the heart,” Dec. 3, 2015) …
“Brown atrophy of the heart is atrophy of the heart muscle (or myocardium) commonly found in the elderly. It is described as brown because fibers become pigmented by intracellular lipofuscin deposits (mostly around the cell nucleus) a type of lipochrome granule.”
The more a local body part “wears and tears,” the more “wear and tear pigment” (lipofuscin) clusters.
Oxygen discourages the growth of cancer, but encourages the acceleration of aging.
Carbon dioxide encourages the growth of cancer, but discourages the acceleration of aging.
Learn to walk the razor’s edge between oxygen and carbon dioxide. It may save your life.
Oxygen slows the growth of cancer, but, if you already have it, speeds its metastasis.
Carbon dioxide speeds the growth of cancer, but slows its metastasis.
Obviously, there must be a third factor empowering an escape from this Catch 22.
Minimizing polyunsaturated fatty acids, highly unsaturated fatty acids, nitric oxide, serotonin, growth hormone, and other inflammatory agents, allows carbon dioxide to grow organs and muscles instead of cancer.
Did I mention growth hormone?
Yes. Eliminating it from the brains of animals has doubled and even tripled their lifespans.
Why doesn’t that ever get mentioned at those Longevity and Anti-Aging Summits?
According to Ray Peat …
“The ‘little mouse,’ and the experiments of Denckla and Everitt, show that a simple growth hormone deficiency or lack of pituitary function can double the life span: Intervention in the many other self-stimulating excitatory pathways can produce additional retardation of the aging process, acting at many levels, from from the extracellular matrix to the brain.”
Why is the pituitary gland called the Master Gland?
Cut it out completely and a salmon lives to spawn another day.
Perhaps the thyroid gland is the Master Gland?
What if the Death Hormone were in the pituitary gland, and the Power of Life and Death were in the thyroid gland?