Hibernation & Torpidation
I’m somewhat north of the cheering section when it comes to Ray Peat’s ideas about sleep and darkness.
On the plus side, he does seem to regard carbon dioxide as Nature’s evening substitute for light as an antidote for the stress of darkness.
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According to Adano Ley (Swami Nitty-Gritty) …
“Accelerate the consciousness with respiration. A person in delta breathes through their bones.”
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A hibernating bear recycles its bone calcium.
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Rachel Nowak (“Bear bones hint at treatment for osteoporosis,” New Scientist, Nov. 29, 2003) wrote …
“Hibernating bears have a unique ability to stop their bones from degenerating during long periods of inactivity, a finding that is stimulating the search for new treatments for osteoporosis.”
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Hibernating animals also have increased antibody and immune responses.
They resist infection, parasitism, cancer, and lethal levels of radiation.
They produce a bone-preserving substance that protects their bones from thinning during hibernation.
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Wayne Lynch (Bears: Monarchs of the Northern Wilderness, 1993) wrote …
“Relating to HIT [Hibernation Induction Trigger] again, research on bears and other hibernators may change the course of two other maladies, cancer and viral infections such as the common cold. Time and again, hibernators injected with pathological viruses have not become ill. And deadly tumour cells inoculated into hibernators have consistently failed to grow. Perhaps if hibernation could be induced in humans, these ailments might reverse their course, or at least be more susceptible to drug therapy. Inducing hibernation in humans is not as farfetched as it sounds. Consider this final bit of research conducted by Dr. Peter Oeltgen, a pathologist at the University of Kentucky. Oeltgen and his colleagues injected HIT into a monkey, an animal that has never been known to hibernate. To the amazement of the researchers, the monkey fell asleep for six hours, its heart rate and body temperature dropped, and its appetite was depressed for over a week. This suggests that all mammals, possibly including humans, may be responsive to HIT.”
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Mark B. Roth & Todd Nystul (“Buying Time in Suspended Animation: An ability to put the human body on hold could safeguard the critically injured or preserve donor organs for transport,” Scientific American, Jun. 2005) wrote …
“Recent studies in our laboratory at the Fred Hutchinson Cancer Research Center in Seattle and by other researchers have shown that hibernationlike states can be induced on demand in animals that do not naturally hibernate. Moreover, such animals seem to be protected from the usual effects of blood loss, such as oxygen deprivation, while they are in a suspended state. These results raise the exciting possibility that suspended animation may be feasible in humans as well. Indeed, the methods our group used to induce suspended animation in lab animals and in human tissue suggest this capability could be latent in many organisms through a mechanism with roots in the earliest days of microbial life on earth.”
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Gordon Grigg & Lyn Beard (“Hibernation by Echidnas in Mild Climates: Hints about the Evolution of Endothermy?,” Life in the Cold: Eleventh International Hibernation Symposium, 2000) wrote …
“Short-beaked echidnas undergo both torpor and hibernation, expressed to different extents in different climates. We propose that when well fed animals hibernate in comparatively mild climates, with food available, they are using the winter cold as a resource and ‘putting themselves on ice’ until the next breeding season. That is, echidnas are hibernating in mild climates for energy advantage, not from energy necessity. We interpret the use of hibernation by echidnas in the more severe climates, where there is a food shortage, as a specialisation of a more general, ancestral capacity. There are also avian, marsupial and eutherian species in which torpor in mild climates appears to be practised for energetic advantage rather than from necessity. The similarity of patterns of hibernation in echidnas, mountain pigmy possums and arctic ground squirrels emphasises the likelihood that torpor and hibernation are plesiomorphic across all three Sub-classes of Mammalia. Attention is drawn to parallels between the daily/seasonal cycles in the body temperatures of torpidators/hibernators and those seen commonly in reptiles, and to the extent to which thermoregulatory mechanisms in reptiles foreshadow those in mammals and birds.”
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According to Adano Ley …
“One atom of oxygen could last you forty years. Live by intracellular osmosis.”
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'Hibernation & Torpidation' have 8 comments
March 27, 2018 @ 4:43 pm Atom
Ray Peat (“Protective CO2 and aging,” 2011) wrote …
“Since queen bees and mole rats live in the dark, I think their high carbon dioxide compensates for the lack of light. (Both light and CO2 help to maintain oxidative metabolism and inhibit lactic acid formation.) Mole rats are believed to sleep very little. During the night, normal people tolerate more CO2, and so breathe less, especially near morning, with increased active dreaming sleep.
“A mole rat has never been known to develop cancer. Their serum C-reactive protein is extremely low, indicating that they are resistant to inflammation. In humans and other animals that are susceptible to cancer, one of the genes that is likely to be silenced by stress, aging, and methylation is p53, a tumor-suppressor gene.”
March 27, 2018 @ 4:46 pm Atom
Nitric oxide was responsible for the AIDS pandemic.
Viagra not only stiffens the male member, it relaxes the (1) anal sphincter and (2) swallowing reflex.
One side effect is the gradual destruction of the immune system.
Who invented the virtues of nitric oxide in the first place?
Big Pharma = Dr. Evil
Who is (99% of the time) a copycat of whatever Big Pharma decrees?
Big Supp = Mini-Me
Big Supp is Toximolecular Medicine Lite.
https://www.youtube.com/watch?v=tkmi_UTsjtE
March 27, 2018 @ 4:47 pm Atom
Do we store fat like a salmon or a codfish?
And is the French way of force-fattening a goose liver (with CORN) healthier for the goose than the Roman way (with DRIED FIGS)?
March 27, 2018 @ 4:50 pm Atom
Hugh Hefner (1926-2017) had a minimum of 240 teaspoons of sugar a day for years in his 30 or so Pepsis a day until he switched to artificial sweeteners.
Is anyone actually reading Otto Warburg instead of reading bloggers who are liberally misquoting him from other bloggers who haven’t read Otto Warburg either?
Is it bloggers on bloggers on bloggers?
“Facts like photographic film — must be exposed before developing.” — Charlie Chan
http://solartiming.com/store–mini-e-books.php#Age-Spots
March 27, 2018 @ 7:26 pm Sean
Atom, I’d love to hear your take on David Wolfe’s take that charcoal is a wonder substance.
March 28, 2018 @ 2:53 am Atom
Although favorably impressed by the overall interview (it was one of the shows that makes One Radio Network Da Bomb), my take on activated charcoal (including C60) hasn’t changed since I wrote “Another Side Of Activated Charcoal” on ORN on Nov. 14, 2016.
(You can access it with ORN’s “search” function.)
The side effects from this new use of activated charcoal (compared to its use in large amounts for acute poisoning) won’t become evident for at least another 20 years, so I’ll be avoiding it until at least 2035. LOL
Meanwhile, Vibrant Gal and I keep a bottle of activated charcoal in our medicine cabinet in case of an emergency.
March 30, 2018 @ 12:40 pm RadioGuGu
How about dental, other topical use/s, not necessarily consuming it each day?
April 1, 2018 @ 11:16 am Atom
Activated charcoal actually damages the teeth.
Activated charcoal is at its best in water filters.
Its use in Shreddies is like mopping up the floor instead of turning off the faucet.
https://www.myshreddies.com/flatulence/mens/